The problem with most blockchains is that they are publicly auditable, and they move slowly.
It turns out, most games need neither of those. Most players don't want their entire inventory to be publicly seen, and most players want transactions to be instant.
The kinds of games that DO work on blockchains, are those that rely on public auditability (think gambling,) and scarcity (think Ethercats.)
Blockchains are a neat computational primitive, but it's fairly limited in scope as it only adds value where you need a public, distributed, consensus among potential adversaries, and you are OK with slower update times, the cost of perhaps choosing the wrong continuation fork for a bit (number of confirmations,) and spending a lot of resources for the "distributed consensus" part.
In 99.9% of games, a single mysql database will work better.
Something which I haven't seen yet, is some kind of smart contract bet which depends on the future outcome of the chain -- say, use the hash number of the next accepted block as the "roll" of the dice for a betting system. Pay 0.1% of prize pools to the operator of the contract; pay 50% of the prize pool into, say, 10% of players each turn, roll 49.9% of the bets to the next iteration, with some one-in-a-million chance to get 500,000x your payment back. Basically, lotto-on-blockchain, using the block hash as presumably un-tamperable RNG.
The shilling of syscoin in the original post aside, if I were to build some gaming infrastructure on a block chain, I'd pick one with a little more maturity. Probably Ether main fork, or perhaps Neo (formerly antshares.) And even so, the main problem with all of these "put your trading on the blockchain!" systems, is that the blockchain has no way to enforce physical compliance for physical assets, and in the end, physical force is what all physical ownership is all about. You couldn't "own" a house unless there existed a police force that would evict people who tried to squat on your property (or you could afford private security, like a feudal lord.)