I appreciate your efforts in using games as a platform to deliver a message. But what message do you want to provide?
I just made up my own categories here to help you clarify:
- therapeutic games - should be developed with scientists. I know folks with other issues such as dyslexia, ADHD and social phobia has "mini-games" in which they can train on very specific tasks (like memory, sounding words etc.) or in the case of phobia - cognitive therapy in a gamification format (you get scores by completing challenges).
- informational games - educating others of how it can be to have issues with this. An example is http://www.kongregate.com/games/jordanmagnuson/loneliness which translates the feeling of loneliness into a little "non-game" as he calls it.
- comforting games - games which people with issues can play where they can feel familiarity with the protagonists, where the UI and in-game experiences have been adjusted/adapted to any deficiencies and things which they might find disturbing.
The thing is each of these games requires their own approaches (educated, emotional/artsy and general game development for a specific user group)