Beside "ransomware" crpto viruses, good old days of dangerous "bootsector and file infecting viruses" are mostly long gone. So I couldn't care less about a malware or adware which I removed thousands of time in my life (at other people's computers ofc). Only I have a habit of disabling autorun and using Windows Explorer right pane to browse flash disks instead of double clicking.
Anyway, most of these antiviruses slow your system more than "virus" itself almost it is better stick with virus. So better educate yourself than hoping that antivirus with catch all of them.