There will never be actions that require a mouse cursor. The mouse can be used in menus, but that is also optional. The gameplay is really suited for dual analog controllers (one for the camera). It still works well with WASD or arrow-key movement, but then you only have 2 fixed speeds (by holding shift to run). You can actually even move around with the mouse - but like pushing the character with motion, not point and click. The character is controlled almost exactly like the newest Prince of Persia games.
As for having the camera in a fixed position, I'm not sure. Small places like this will be very rare. They're just houses. And even then, you're probably looking at the smallest house in my game. I could fix the camera in-doors only, but then you run into nefthy's complant when traveling inside or out, the camera shifts into it's fixed location.
Thanks again for the suggestions
edit: In case anyone is curious, here's the outside. Also heavily WIP, though: