Unreal and Unity is the good one. Or visit mobilegamegraphics.com for more ideas in creating Isometric games.

Thanks to all of you.

I started with ue4. Not easy :unsure:

If UE4 isn't easy for you, bud, then you're not ready for game development :/
It's great, because through the Blueprints system you don't HAVE to know how to write C++ code, and there are TONS of community-based plugins for it.
Really though, just hit up the tutorials! There are TONS of them to walk you through from your first time opening UE4 to finishing a basic top-down game.

And for a 2D Platformer that teaches you a LOT about the Paper2D engine and holds your hand while reminding you to look both ways while you cross the road: