Hmm, just thinking, but imagine this :
There is a map/playing area/mad scientist's lab where the evolution happens, and multiple players have god/scientist/gamer-options to manipulate this environment;
in a challenging mode they would all try to develop a certain kind of creature(each a different one) while the environment only has enough living space to support only (maybe players minus one, maybe only one) creatures.
There could be a coöp-mode where 2 or so players both try to evolve some kind of creature, both of them are going for a different creature(some kind of challenge they both individually want to accomplish) and maybe they only succeed if they are succeeding both at the same time(make sure bad players won't be making the starting levels impossible to come through)
A free/sandbox mode is off course standard in such a game.