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[quote name='Khaiy' timestamp='1296857586' post='4769743']
I assume you're responding to my post responding to mikeman. My point in that post was that cancer is not a problem of non-cancerous cells in the vicinity of cancerous ones being not competetive enough, as increased competition from other cells would be worse than cancer, not better, because once cells fight amongst each other for resources the destruction of the host organism is guaranteed.
The sharing DNA part is a pretty big consideration to consider things "apart" from. But here's my reasoning:
1. Resources don't have anything to do with the reproductive advantage of a cancerous cell, nor do they compete any better for the resources that are there. You can make the argument (as you are) that the abundance of resources in a human body coupled with the lack of interest of the top-down control structure in managing cancerous cells creates a very special niche which any cell can exploit by reproducing a ton, but.
2. Unlike organisms in a given environment, cells have very specific functions.
2a. All functions of all cells are expressly for the continuation of the overall organism, with the payoff for the cells being the continued introduction of resources. As soon as cancer develops, it guarantees that this process will end. A cell line could continue forever if the organism continued to thrive, and even though cancer isn't the only possible end to thriving, the organism doesn't move past it. It's only in the last few decades that many people have lived long enough to die of cancer, but if you live long enough you will develop it, and if nothing else kills you, cancer will.
3. Genetic traits are not limited to a single organism. If you look at the lineage of cells through generations of organisms, non-cancerous cells are vastly more numerous than cancerous ones. Genetic similarity of parent to child declines by half with each generation, but one genetic difference that is never passed from one generation to the next is an inferior copy of (or lack of) the p53 and RAS oncogenes. Cancerous cells are not more successful at persisting through time and through successive generations than non-cancerous ones.
1. Yes they do.
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I could have been clearer here. The cancerous cells do indeed need resources to reproduce. But they do not have any better access to resources, are not better at absorbing or using them, than any other cells. The reason that they reproduce more is not based on resources-- the level of resources that they have access to is pretty consistent over time, and cetianly the same as non-cancerous cells.
2. So do organisms in an environment.
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False. Organisms in an environment fill a niche, which is controlled by probabilities and a normal distribution of variants on existing organisms. An organism takes its place in a dynamic equilibrium, but they do not exist nor have have they evolved to serve a single (or set) of function(s). As conditions in an environment change, you can see a change in relative frequencies of traits in a species in response. Cells in your body are the same and perform the same functions in the same way regardless of other factors.
2.a. No they are not. A liver cell does not think, "Oh damn this dude is drinking a lot so I better work extra hard so he can feel good and every cell in the body can live longer," it just does it's job. For all it knows it could be outside the body as long as it's still getting everything it needs to survive. It just so happens that what it does is beneficial to the whole system and the whole organism can live longer.
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You're arguing my point, particularly with your statement that cells have "jobs" and that they will continue to do those jobs "as long as [they] are still getting everything [they] need to survive". It does not "just so happen" that cellular functions benefit the overall organism. Organs are refinements of precursor structures that existed in ancestors of a current organism. Their functions have been refined because they benefit the entire organism, allowing it to reproduce more or better. A liver that's better at being a liver doesn't do anything for the liver itself, because it's only at the organismal level that function brings extra resources or other measures of fitness. No, a liver does not "think", because thinking is irrelevant. A liver that is less effective reduces fitness of the organism that contains it, and is less likely to be passed on.
3. They do in the sense of a body being the environment. If we over-reproduced and killed our planet by using up or blowing up all the resources we would all die just like cancer cells die when the body dies.
You are still looking at cells as cells. To understand the analogy look at a cell as an organism and the body as the environment.
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Cells are cells. No matter how nice or convenient your analogy might be for your point, cells are like cells more than they are like anything else, because they are cells. An analogy that requires they shed their cell-like characteristics to be replaced by some other characteristics is going to break down at some point, and we've certainly reached that here. I understand your analogy, but it doesn't work at the level of precision you're trying to apply. Cells cannot reproduce independently of the overall body, and cannot even live independently. A squirrell can move from one ecosystem to another if it feels like it. Your pancreas cannot.
You seem like you're a big proponent of Lovelock. If you really like the idea of Gaiaology then go ahead and frame things that way. But cells are part of a finite open system, and contain the entire genome of that system, and are streamlined (more or less) by statistical considerations such that a type of cell behaves in one way, essentially static. The earth is a massive closed system, with incredible dynamic forces on genetic diversity regardless of current conditions. There are so many differences between the earth and a human body that repeating "They're the same, just think about them as if they were the same" isn't going to cut it.
Plus, life on the earth has (and will continue to) recover from a lot-- even if you think that the earth "lives", it certainly doesn't do so in any way similar to the organisms on it. Life continues on the planet after dramatic events like mass extinctions, and niches that are left vacant for any reason will eventually be filled by something, even if it's just a novel kind of bacterium.
If, as you seem fond of repeating, humans over-used resources to the point that the planet could no longer sustain human life, that wouldn't be the end of life on Earth. Our corpses would leave ample material for other organisms, be they scavenging animals or humble bacteria. Even if humans ate all of the food that we can eat, the feces we produced would nourish record numbers of microorganism species, whether or not the humans continued on. Will that happen with the cells in your body? Of course not. Once the organism dies, everything that made it up will die, despite the presence of the same abundance of material resources.
[quote name='Khaiy' timestamp='1296857586' post='4769743']
If you want to look at a single organism at a time, you can look at cancerous cells as superior in the sense that they reproduce faster. But they are not different from other cells in any other "competitive" capacity. And the strategy that they follow is not possible in any environment other than the one that they inhabit, which is almost entirely absent of selection pressures. So any analogy that you make to other environments isn't going to go very far, because no other environment is like a multicellular organism.
Faster reproduction is a HUGE competitive advantage. It's absolutely astronomical in how big a competitive advantage it is.
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Faster reproduction is indeed a successful strategy in many situations (although not a cut-and-dried "advantage"). However, cells that make up an organism do not compete with each other as different organisms do. Reproductive and genetic factors do not apply to cells in an organism in the same ways that they do amongst organisms, because they do not reproduce in the same way nor do they face tests of fitness in the same way.
and I'm not so sure you have argued quite well enough to nullify the Terrestrial organisms:Earth::Cells:People analogy. Every organism serves it's purpose in the environment of the earth.
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See above for clarification, I don't want to re-type why Gaiaology and a dynamic equilibrium of limitless types of organisms responding to shifting conditions at any given time is different from organism-level fitness enforcing specific behaviors on limited varieties of cells in symbiotic-style communities. Your position oversimplifies the concepts evolution and population biology while mis-applying them. If your position reflected the reality of natural selection or population biology, then I might agree with your conclusion that cancerous cells are more fit because they reproduce more. But your position does not reflect the realities of those things.